- ZDI stands for Zero Day Initiative (3Com/Tippingpoint)
- ZDI stands for Zimbabwe Defence Industries
- ZDI stands for Zamojska Dyrekcja Inwestycji (Polish: Zamosc Investment Management; Zamosc, Poland)
- ZDI stands for Zilog Debug Interface (debugging software)
- ZDI stands for Zentrale Dienste Informatik (German: Central Services Computer Science)
- ZDI stands for Zentralverband Deutscher Ingenieure eV (German: Central Association of German Engineers; Munich, Germany)
- ZDI stands for Zamudio Data Information Systems (California)
ZDI