- DSIR stands for Department of Scientific and Industrial Research (various countries)
- DSIR stands for Division of Services and Intervention Research (US NIH)
- DSIR stands for Defected Stepped-Impedance Resonator (electrical engineering)
- DSIR stands for Designer of Small Interfering RNA (bioinformatics)
- DSIR stands for Dance Self-Instruction Record
- DSIR stands for Director Space and International Regulatory Activities (Canada)
- DSIR stands for Demand-Side Increasing Returns
- DSIR stands for Dead Skunk In Road
DSIR