- DSPE stands for Département de la Sécurité, de la Police et de l’Environnement (French: Department of Homeland Security, Police and the Environment; Switzerland)
- DSPE stands for Droit Spécifique sur les Perles Exportées (French: Specific Duty on Exported Pearls)
- DSPE stands for Dispersive Solid Phase Extraction
- DSPE stands for Dry Solid Polymer Electrolyte
- DSPE stands for Division System Product Engineer
- DSPE stands for Division of Special Education (Botswana Ministry of Education)
- DSPE stands for Digital Signal Processing Electronics
- DSPE stands for Direcção de Serviços de Prospectiva Estratégica
DSPE