- ACRU stands for American Civil Rights Union
- ACRU stands for Avionics Cooling Refrigeration Unit (aviation)
- ACRU stands for Agricultural Catchments Research Unit (University of Natal; South Africa)
- ACRU stands for American Civil Responsibilities Union (California)
- ACRU stands for Active Confirmed Registered User (eBay)
- ACRU stands for Asbestos Contractors Registration Unit (San Francisco, CA)
- ACRU stands for Aged Care Rehabilitation Unit
- ACRU stands for Automatic Capsule Rejection Unit
ACRU