- AFACS stands for A-Files Accountability and Control System (US INS)
- AFACS
- AFACS stands for Academy for Forensic Application of the Communication Sciences
- AFACS stands for Association des Femmes Africaines Chrétiennes de Suisse (Switzerland)
- AFACS stands for Army Forward Area Calibration System
- AFACS stands for Association Franco-Arménienne de Coopération Scientifique
- AFACS stands for Association Franco Algerienne pour la Culture et La Solidarité
- AFACS stands for Asbestos Fibers Automatic Counting System
- AFACS stands for Associate Fellow, American College of Surgeons
- AFACS stands for Avionics Forced Air Cooling System
AFACS