- AFDE stands for Association Française des Dysplasies Ectodermiques (French: French Ectodermal Dysplasia Association)
- AFDE stands for Association Française du Déménagement d’Entreprises (French: French Association of Moving Companies)
- AFDE stands for Association of Forensic Document Examiners (est. 1986)
- AFDE stands for Aft Flight Deck Equipment
- AFDE stands for American Fund for Dental Education (scholarship group)
- AFDE stands for Arctic Fuel Dispensing Equipment
AFDE