- AFDM stands for Ash Free Dry Mass
- AFDM stands for Medium Auxiliary Floating Dry Dock (Non Self-Propelled)
- AFDM stands for African Diamond Company, Inc. (stock symbol)
- AFDM stands for Aboriginal Family Decision Making (indigenous initiative; Australia)
- AFDM stands for Advanced Fluid Dynamics Model
- AFDM stands for Alianza Federal de Mercedes (Spanish: Federal Alliance of Land Grants; Mexico)
AFDM