- AFEM stands for Armed Forces Expeditionary Medal
- AFEM stands for Adaptive Finite Element Method (mathematics)
- AFEM stands for Autonomous Foreign Exchange Market (est. 1995)
- AFEM stands for Alliance for Fire and Emergency Management
- AFEM stands for Association des Femmes Éducatrices du Mali (French: Association of Women Educators in Mali)
- AFEM stands for Air Force Emergency Management (US Air Force)
- AFEM stands for Ansvar for Egen Mestring (Norwegian: Responsibility for Self Mastery)
AFEM