- AFFF stands for Aqueous Film Forming Foam
- AFFF stands for Amsterdam Fantastic Film Festival
- AFFF stands for Agent Formant un Film Flottant (French: Film Forming Foam Agent)
- AFFF stands for Aqueous Fire Fighting Foam
- AFFF stands for Asian Festival of First Films (est. 2005)
- AFFF stands for Asymmetric Flow Field-Flow Fractionation (chromatography technique)
- AFFF stands for AKR’s Free Form Framework
AFFF