- AFFL stands for American Fantasy Football League
- AFFL stands for Above Finished Floor Level (building plans)
- AFFL stands for A Friend For Life
- AFFL stands for Anime Fanfiction Links
- AFFL stands for Agency For Foreign Languages
- AFFL stands for Affiliate/Affiliation
- AFFL stands for above fixed floor level (architecture)
- AFFL stands for Australian Fantasy Football League
- AFFL stands for Arena Flag Football League
- AFFL stands for Association for the Future of the French Language
- AFFL stands for Australian Forest Funds Limited
- AFFL stands for American Family Friendly Libraries (American Library Association)
AFFL