- AFIS stands for Automated Fingerprint Identification System
- AFIS stands for Association Française pour l’Information Scientifique (French: French Association for Scientific Information; est. 1968)
- AFIS stands for Aerodrome Flight Information Service
- AFIS stands for Armed Forces Radio and Television Service
- AFIS stands for Automated Fingerprinting Identification System (Pakistan)
- AFIS stands for Agribusiness and Farm Insurance Specialist (professional designation)
- AFIS stands for Air Force Intelligence Service
- AFIS stands for Amministrazione Fiduciaria Italiana della Somalia (Italian Trusteeship of Somalia)
- AFIS stands for Airborne Flight Information System
- AFIS stands for Airborne Flight Information Service
- AFIS stands for Anti-Fraud Information Service
- AFIS stands for American Forces Information Service/System
- AFIS stands for Air Force Intelligence System
AFIS