- AFME stands for Association for Financial Markets in Europe (est. 2009)
- AFME stands for Association Française de Médecine Morpho-Esthétique et Anti-Âge (French cosmetic surgery association)
- AFME stands for Armed Forces Medical Examiner (US DoD)
- AFME stands for Association Française des Médecins Esthéticiens
- AFME stands for Africa and the Middle East
- AFME stands for Agent Factory Micro Edition (mobile device platform)
- AFME stands for Alliance Franco-Marocaine d’Essaouira (French: Franco-Moroccan Alliance of Essaouira; Essaouira, Morocc
AFME