- AFOB stands for Acoustic Festival of Britain (UK)
- AFOB stands for Archaeological Fieldwork Opportunities Bulletin
- AFOB stands for American Foundation for Overseas Blind (now Helen Keller International)
- AFOB stands for A Fistful of Boomstick (video game)
- AFOB stands for A Fountain of Bargains (online shopping directory)
- AFOB stands for Anchorage Federal Office Building (Anchorage, AK)
AFOB