- AFPAC stands for Algebraic Frames for the Perception-Action Cycle (workshop)
- AFPAC stands for Association Française pour les Pompes A Chaleur (French; Paris, France)
- AFPAC stands for Anglo-French Physical Acoustics Conference
- AFPAC stands for Air Forces Pacific
- AFPAC stands for Armed Forces Program on AIDS Control (Nigeria)
- AFPAC stands for Armed Forces, Pacific
- AFPAC stands for America First Political Action Conference
AFPAC