- AFSA stands for American Foreign Service Association
- AFSA stands for American Financial Services Association
- AFSA stands for American Fire Sprinkler Association
- AFSA stands for Air Force Sergeants Association
- AFSA stands for Adoption and Safe Families Act of 1997 (law)
- AFSA stands for American Federation of School Administrators
- AFSA stands for Armed Forces Security Agency
- AFSA stands for Arbitration Foundation of Southern Africa
- AFSA stands for American Fibromyalgia Syndrome Association, Inc.
- AFSA stands for Australian Fertiliser Services Association
- AFSA stands for Air Force Safety Agency
- AFSA stands for Association Française du Syndrome d’Angelman
- AFSA stands for American Federation of Strength Athletes
- AFSA stands for Afghan Student Association
- AFSA stands for Alternative Force Structure Assessment
- AFSA stands for Association of the French Schools in North America (est. 1985)
- AFSA stands for Association Française des Semences Autogames (French)
AFSA