- AFSO stands for Air Force Smart Operations
- AFSO stands for Autism Family Support Oxfordshire (Oxfordshire, UK)
- AFSO stands for Assistant Facility Security Officer
- AFSO stands for Afghan Football Support Organization (Newark, CA)
- AFSO stands for Air Force Special Ops (New Zealand)
- AFSO stands for Australian Geological Survey Organisation
- AFSO stands for Aviation Fluids Services Officer (Canadian Air Force)
AFSO