- AFSR stands for Association Française du Syndrome de Rett
- AFSR stands for Association Franco-Suédoise pour la Recherche (French)
- AFSR stands for Argonne Fast Source Reactor (Argonne National Laboratory)
- AFSR stands for Armed Forces of South Russia
- AFSR stands for Asynchronous Fault Status Register (computer architecture)
- AFSR stands for Analog Feedback Shift Register
- AFSR stands for Algebraic Feedback Shift Register
- AFSR stands for Air Force Survival Rifle
- AFSR stands for Air Force Service Registry (implementing Service Oriented Architecture)
AFSR