- C2W stands for Command and Control Warfare (US DoD)
- C2W stands for Chip-to-Wafer (computer chip design)
- C2W stands for Climate-to-Weather Disaggregator (climatology)
- C2W stands for Chemisch 2 Weekblad (Dutch chemistry journal)
- C2W stands for Christ to the World Ministries, Inc. (est. 1991; Morley, MO)
- C2W stands for Created 2 Worship (Christian music group)
C2W