- CAFE stands for Corporate Average Fuel Economy
- CAFE stands for Clean Air for Europe
- CAFE stands for Cannabis and Fine Edibles (Toronto, Ontario, Canada)
- CAFE stands for Host America Corporation (stock symbol; formerly HAC)
- CAFE stands for Conventional Armed Forces in Europe
- CAFE stands for Comparative Aircraft Flight Efficiency Foundation (California)
- CAFE stands for Canadian Association of Family Enterprises (Kingston, ON, Canada)
- CAFE stands for Consolidated Application Foundation for Eclipse (Java development)
- CAFE stands for Conditional Access for Europe (electronic payment system)
- CAFE stands for Conduit Artery Function Evaluation
- CAFE stands for Ciudadanos Activos de Formación Electoral (Spanish: Active Citizens Electoral Training; Guatemala)
- CAFE stands for Conservatives Against a Federal Europe (UK)
- CAFE stands for Camaradas, Arriba Falange Española! (Spanish political slogan)
- CAFE stands for Coffee and Farmer Equality
- CAFE stands for Ciències de l’Activitat Física I l’Esport (Catalonia)
- CAFE stands for Community Alliance of the Far Eastside (Indiana)
- CAFE stands for Communications Access for Everyone
- CAFE stands for Concepts to Application in System-Family Engineering
- CAFE stands for Computer Algebra & Functional Equations
- CAFE stands for Communications Automation Follow-On Effort
- CAFE stands for Central Australian Fronts Experiment
- CAFE stands for Clarity Audio Front End
- CAFE stands for Canadian Association of Fairs & Expositions
- CAFE stands for Canadian Association of Fish Exporters
- CAFE stands for Collateral Artery Flow Exercises
CAFE