- DPSO stands for Décoration Peinture du Sud Ouest (French: Decorative Painting in the South West)
- DPSO stands for Dropping Purple Smoke Outfit
- DPSO stands for Dropping Purple Smoke Online (gaming community)
- DPSO stands for Dissipative Particle Swarm Optimization
- DPSO stands for Discrete Particle Swarm Optimisation
DPSO