- DRDC stands for Defence Research and Development Canada (formerly Defence Research and Development Branch)
- DRDC stands for Dairy Research and Development Corporation
- DRDC stands for Dark River Derby Coalition (Quincy, IL)
- DRDC stands for Darfur Relief and Documentation Centre (Geneva, Switzerland)
- DRDC stands for Detector Research and Development Committee (Switzerland)
- DRDC stands for Denver Reception Diagnostic Center (Department of Corrections)
- DRDC stands for Defence Regional Distribution Centre (UK)
- DRDC stands for Dixie Round Damce Council
- DRDC stands for Delaware Repertory Dance Company (University of Delaware)
DRDC