- DSME stands for Diabetes Self Management Education
- DSME stands for Daewoo Shipbuilding & Marine Engineering Co., Ltd.
- DSME stands for Division of Science and Mathematics Education (Michigan State University)
- DSME stands for Department of Science and Mathematics Education
- DSME stands for Dimensionnement des Structures Mécaniques dans Leur Environnement (French: Design of Mechanical Structures in Their Environment)
- DSME stands for Digital Systems Middle East
- DSME stands for Devenus Sourds et Mal Entendants (French: Deaf and Hard of Hearing)
- DSME stands for Domain-Specific Modeling Environment
- DSME stands for Division of Studies in Medical Education
- DSME stands for Dark Slayer Mutation Engine (polymorphic virus)
- DSME stands for Device State Management Entity
- DSME stands for Diabetic Self-Management Education
- DSME stands for Directory Services Management Exit
- DSME stands for Director of Student Medical Education
- DSME stands for Department of Studies in Medical Education (University of Alberta; Canada)
- DSME stands for Defence Submarine Engineering
- DSME stands for Distinguished Sales and Marketing Executives (award)
- DSME stands for Domain-Specific MIPS Environments
- DSME stands for Durban Society Model Engineers (South Africa)
- DSME stands for Drewsif Stalin’s Musical Endeavors (band)
- DSME stands for Damn Smart Mail Enterprise
- DSME stands for Division for Stewardship and Mission Education
- DSME stands for Diabetes Self Monitoring Education
- DSME stands for Dual Shape Memory Effect (metals)
- DSME stands for Department for Surface Mining and Enforcement
DSME