- DTFS stands for Discrete-Time Fourier Series (mathematics)
- DTFS stands for De Twentsche Fornuizenspecialist (Dutch: Twentsche Cookers Specialist)
- DTFS stands for Desktop File System
- DTFS stands for Domestic Toll Free Service (telecommunications; various companies)
- DTFS stands for Deutsch-Tschechische Fussballschule (German: Czecho-German Football School )
- DTFS stands for Days to First Service (genetics)
- DTFS stands for Direct Tape File System
- DTFS stands for Dial Tone Feature Set
DTFS