- DUSC stands for Downtown United Soccer Club
- DUSC stands for Drug Utilisation Sub Committee (Department of Health and Ageing; Australia)
- DUSC stands for Durham University Solar Car (Durham University; Durham, England, UK)
- DUSC stands for Dartmouth United Soccer Club (Canada)
- DUSC stands for Delhi University South Campus (New Delhi, India)
- DUSC stands for Directory Update Service Center
DUSC