- YPK stands for Young Professionals of Knoxville (Knoxville, TN)
- YPK stands for Young Professionals Kesher (Jewish organization; Washington DC, Maryland and Virginia)
- YPK stands for Yersinia Pestis KIM (genome sequence)
- YPK stands for Yayasan Pengembangan Kawasan (Indonesian: Regional Development Foundation)
- YPK stands for Yeast Pyruvate Kinase (biochemistry)
- YPK stands for District Barge, Pontoon Stowage (US Navy)
- YPK stands for Yen Pilch Komadina and Flemming (Phoenix, AZ)
YPK