- YRC stands for Yellow Roadway Corporation
- YRC stands for Youth Research Centre (University of Melbourne; Melbourne, Victoria, Australia)
- YRC stands for York Railway Company
- YRC stands for Yeast Resource Center (National Center for Research Resources; Department of Biochemistry; Department of Genome Sciences; University of Washington)
- YRC stands for Yokohama Rubber Company, Ltd.
- YRC stands for District Chamber, Submarine Rescue (US Navy)
- YRC stands for Yantic River Consultants, LLC (Connecticut)
- YRC stands for Yerkes Research Center (Atlanta, GA)
YRC