- ZS stands for Zoological Society (UK)
- ZS stands for Source Impedance
- ZS stands for Zend Studio (Zend)
- ZS stands for Zellweger Syndrome
- ZS stands for Zero Scale
- ZS stands for Zombie Squad
- ZS stands for Zeptosecond (10 to the power -21 of a second)
- ZS stands for Zagat Survey
- ZS stands for Zamil Steel
- ZS stands for Zürcher Studentin (student newspaper in Zürich, Switzerland)
- ZS stands for Zeitsoldat (German)
- ZS stands for Zelda: Mystery of Solarus (game)
- ZS stands for Zakharov-Shabat (scattering)
- ZS stands for Zero and Subtract
- ZS stands for Navy Airship Scouting Squadron (US Navy aviation unit designation used from 1920s to 1940s)
- ZS stands for Zonal Slot
- ZS stands for Zoltner and Sinha (founders of ZS Associates, a global management consulting firm)
ZS