- AFSE stands for American Friends Service Committee (Quakers; Philadelphia, PA)
- AfSE
- AFSE stands for Automotive Functional Safety Expert (qualification)
- AFSE stands for Association Française de Sciences Économiques
- AFSE stands for Association Franco-Slave des Etudiants
- AFSE stands for All Fuels and Energy Company (Johnston, IA)
- AFSE stands for Association Française du Syndrome d’Evans
- AFSE stands for Angel Flight Southeast, Inc.
- AFSE stands for Association of Financial Services Educators Ltd (Australia)
- AFSE stands for Association of Future Science Educators
- AFSE Association of Engineering Firms Practicing in the Geosciences
- AFSE Association of Field Service Employees
- AFSE Association of Field Staff Employees
AFSE