- DREB stands for Dehydration-Responsive Element-Binding (biology)
- DREB stands for Défense Rapprochée des Engins Blindés (French: Close Defense of Armored Vehicles)
- DREB stands for Doyle and Roman Enrichment Broth (microbiology)
- DREB stands for Dystrophic Recessive Epidermolysis Bullosa (inherited disease)
DREB