- DUDE stands for Dossier Unique du Demandeur d’Emploi (French: Unique Record of a Job Seeker)
- DUDE stands for Differential Unicode Domain Encoding
- DUDE stands for Disabled United in Direct Empowerment (Medford, OR)
- DUDE stands for Discrete Universal Denoiser
- DUDE stands for Database Unloading by Data Extraction (Oracle)
- DUDE stands for Douglas Underage Drinking Enforcement (Douglas County, Nevada)
- DUDE stands for Defecating, Urinating, Drinking, Eating (physical examination)
DUDE