- DWE stands for Department of Water and Energy (Australia)
- DWE stands for Drill Weekend (US DoD)
- DWE stands for Department of Workforce Education (Arkansas)
- DWE stands for Doppler Wind Experiment
- DWE stands for Double Wing Express (shipping)
- DWE stands for Designers Weekend (Belgium)
- DWE stands for Desired Weapons Effect (US DoD)
- DWE stands for Douglas Wright Engineering Building (University of Waterloo)
- DWE stands for Difficulty with Evacuation
- DWE stands for Deferred Work Element
- DWE stands for Duration Weighted Exposure
- DWE stands for Damit Worley Engineering (Brunei)
- DWE stands for Dakota Wind Ensemble (Sioux Falls, SD)
- DWE stands for Detailed Work Estimate (software engineering/management)
DWE