Posted in Internet Slang, Organizations YFO stands for Youth and Family Outreach (Portland, ME) YFO stands for Your Fly’s Open YFO Share Pinterest Tweet Whatsapp Post navigation YFNXYFNWR Leave a Reply Cancel replyYour email address will not be published. Required fields are marked *Comment * Name * Email * Website Save my name, email, and website in this browser for the next time I comment.